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publicationDate 1986-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0171260-A2
titleOfInvention Hepatitis B vaccine
abstract A polypeptide vaccine is disclosed with the amino acide sequence of Asp-Pro-Arg-Val-Arg-Gly-Leu-Try-Phe-Pro-Ala-Gly-Gly-Ser-Ser-Ser-Gly-Thr-Val that bears the receptor for polymerized human serum albumin capable of raising antibodies to inhibit the access and entry of hepatitis B virus (HBV) to hepatocytes. The polypeptide vaccine is also shown in which the 9th amino acid residue (Phe) is replaced by leucine.
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