abstract |
Steroids of the formula: <IMAGE> <IMAGE> +TR <IMAGE> which are characterized by a 17 alpha -cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or ethynylmethyl substituent and a 17 beta -hydroxy/esterified hydroxy substituent. The steroids of this invention have glucocorticoid, anti-glucocorticoid, progestational, or anti-progestational activity, depending on the particular structure. |