abstract |
7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula ##STR1## wherein R 1 is lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, A is --CH═CH-- or --(CH 2 ) 2 --, n is 1 to 4, m is 1 to 8, and R 2 is ##STR2## wherein R 4 is H or lower alkyl and including all steroisomers thereof. n The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease. |