http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4604403-A

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filingDate 1984-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1986-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a10c71c995e5d440e1a26f0d55dcef4
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publicationDate 1986-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4604403-A
titleOfInvention Use of substituted-3(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treating grey matter edema
abstract The invention relates to novel substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-dio nes, their analogs and their salts. These compounds are synthesized by methods selected from a number of synthetic routes depending on the particular structure, choice of intermediate or preferred reaction sequence. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydrocephalus, post-operative brain injury trauma, edema due to cerebral infections and various brain concussions.
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Total number of triples: 485.