http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4562177-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51a0c49e5390c69aa92b87c3a892344c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 |
| filingDate | 1983-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1985-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_517c30eb08d3270d9bc62b2e53fabc7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2afb9299cc7c67e339c0a9784122c89 |
| publicationDate | 1985-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4562177-A |
| titleOfInvention | 3'-Amino-2' halo-anthracycline antibiotics |
| abstract | Compounds of the formula ##STR1## wherein R 1 is a hydrogen atom or a hydroxyl group; R 2 is a hydrogen atom or a hydroxyl or methoxyl group; X is a fluorine, chlorine, bromine or iodine atom; one of Y and Y' is a hydrogen atom and the other is a hydrogen atom or a hydroxyl or acyloxy group; R 3 and R 4 are each independently a hydrogen atom, an alkyl group, a halo- or phenyl-substituted alkyl group, an acyl group or a halo- or phenyl-substituted acyl group or R 3 and R 4 together form a polymethylene chain having 4 to 6 carbon atoms, are useful as anti-tumor agents, especially for treating leukemia; in particular these compounds exhibit high antileukemic activity against P388 murine leukemia. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4965352-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5374711-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4839346-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5625043-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5237055-A |
| priorityDate | 1982-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.