| abstract |
Substituted isoquinolines of the formula <IMAGE> I wherein R is a lower alkoxy, n is the integer zero or 1, and A is <IMAGE> <IMAGE> +TR <IMAGE> wherein R1 is phenyl halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and pharmaceutically acceptable acid addition salts thereof, are described. The compounds of formula I are useful in the treatment of cerebral and cardiac ischemias. |