| abstract |
Cephalosporin broad spectrum antibiotics represented by the formula <IMAGE> wherein R' is an amino-substituted 5- or 6-membered nitrogen heterocyclic ring, eg. 2-aminothiazol-4-yl and 3-aminopyridin-1-yl; R'' is hydrogen, C1-C4 alkyl, a carboxy-substituted alkyl or cycloalkyl group, or a carbamoyl or substituted carbamoyl group; and R1 and R2 are hydrogen, C1-C4 alkyl, mono or di(C1-C4 alkyl)amino, mono or di(hydroxy-substituted C2-C4 alkyl)amino; are provided. These betaine cephalosporins are provided in antibiotic formulations and are useful in a method for treating infections. |