abstract |
Mammalian collagenase is inhibited by compounds having the formula ##STR1## and salts thereof, wherein R 1 is hydrogen or alkanoyl of 2 to 10 carbon atoms; n R 2 is hydroxy, amino, or ##STR2## R 3 is hydrogen, alkyl of 1 to 4 carbon atoms, ##STR3## R 4 is hydroxy, amino, arginine, leucine, glutamine, alanine or glycine; and n m is 0 or an integer of 1 to 9. |