http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4248874-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18 |
| filingDate | 1980-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1ecdef04c563cda65cc6d0e4f75c8dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b6cb5a09d0e3c98b8969b885990f48 |
| publicationDate | 1981-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4248874-A |
| titleOfInvention | Benzopyrano compounds as antiglaucoma agents |
| abstract | A method of reducing intra-ocular pressure in mammalian patients comprising administering to a glaucoma patient a therapeutically effective amount of a compound of the formula <IMAGE> wherein, in the C ring, X is CH2, S, <IMAGE> or NR4 where R4 is H, loweralkyl, loweralkenyl, loweralkynyl or loweralkanoyl; n is an integer of 0 to 3; m is an integer of 0 to 3, or the C ring is a quinuclidine ring <IMAGE> each R1 is loweralkyl, and when taken together, the substituents R1R1 form oxygen; R2 is a C1-C20 straight or branched chain alkyl, cycloalkyl, or <IMAGE> wherein Y is a straight or branched chain alkylene group having from 1 to 10 carbon atoms, and each R5, R6 and R7 are the same or different members of the group consisting of H, halo or loweralkyl; R3 is H or <IMAGE> wherein Y' is a straight or branched chain alkylene group having 1 to 8 carbon atoms, a is an integer from 1 to 4, b is an integer from 1 to 4, Z is CH2, O, S or NR9 where R9 is H or loweralkyl, with the provision that when Z is O, S or NR9, the sum of a and b is 3 or 4, and R8 is H or loweralkyl; and the pharmaceutically acceptable salts thereof. |
| priorityDate | 1976-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 159.