| abstract |
A chewing gum is provided which is capable of releasing into the oral cavity relatively large amounts of finely-divided water-insoluble therapeutic materials, which chewing gum includes a water-soluble phase formed of aqueous softener, and the finely divided therapeutic component to be released, said therapeutic component being coated with a water-soluble coating agent for preventing resorption of therapeutic component back into the gum base and, optionally, a first sweetener, dispersed throughout the aqueous softener, and a relatively water-insoluble phase formed of a plurality of separate and distinct masses suspended in and dispersed throughout the water-soluble phase, each of said masses formed of particles of gum base and, optionally, particles of a second sweetener, suchas mannitol and/or sorbitol or sugar, enveloped by particles of gum base. Upon chewing the above gum, the therapeutic component is, in fact, released in the oral cavity in relatively large quantities, together with the aqueous softener. The therapeutic component to be released may comprise orally beneficial materials, such as dicalcium phosphate, antacids, such as magnesium hydroxide, calcium carbonate, as well as vitamins, drugs and the like. In a preferred embodiment, the therapeutic component is coated with gum arabic to facilitate release from chewing gum. |