| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bffad7ab7d8d258bbb55916c0d8aa55a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate |
1975-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1977-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c11750da3ef542fcafc012d70faf935 |
| publicationDate |
1977-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4017614-A |
| titleOfInvention |
Compositions for the relief of migraine |
| abstract |
The invention is predicated on the discovery that certain 1,4-disubstituted piperazines interact synergistically with certain known analgesics to antagonize or block the stimulus causing migraine. This effect is most pronounced when administering a mixture of 1-p-chlorobenzhydryl-4-p-(tertiary butyl)-benzyl-piperazine (buclizine) and N-acetyl-p-aminophenol (paracetamol) in the respective proportions by weight of from 1:20 to 1:200. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4307073-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2488135-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6642243-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9748390-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4428951-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006222601-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4528178-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5972916-A |
| priorityDate |
1969-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |