http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-705979-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aacfd4bbc2258b20dcb7ae8ca4829ec7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-03 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-073 |
| filingDate | 1952-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1954-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-705979-A |
| titleOfInvention | 1.4-aralkyl piperazines and process for the preparation thereof |
| abstract | The invention comprises 1:4 aralkyl-piperazines in which the 1- and 4- positions are substituted by different aralkyl groups and the 2- and 5- positions may be substituted by alkyl radicles, and a process for preparing them by the reaction between an aralkyl halide and a 1-aralkyl piperazine, or by the reaction between an aldehyde and a 1-aralkyl-piperazine followed by reduction. In examples, 1-benzhydryl-4-benzyl-piperazine is prepared by the reaction between benzyl piperazine and benzhydryl chloride, benzhydryl-piperazine and benzyl chloride, and between benzhydrylpiperazine and benzaldehyde, followed by reduction; substituted derivatives obtainable by similar methods include the 1-p-chlorbenzhydryl-4-p-methoxybenzyl, 1-p-chlorobenzhydryl-4-benzyl, 1-p-bromobenzhydryl - 4 - benzyl-, 1 - p - p1 - di chlorobenzhydryl-4-benzyl-, 1-p-methylbenzhydryl-4-benzyl-, and other combinations of methoxy, ethoxy, methyl-, propyl-, butyl-, chloro- and bromosubstituted products; and by selecting as piperazine derivative one having alkyl groups on the 2- and 5- carbon atoms as starting material, similar products to the above derivatives are also obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-000635-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9628440-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4663325-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5646149-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3318876-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4017614-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5545645-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5428037-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9424116-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9515958-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0159566-A1 |
| priorityDate | 1951-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.