abstract |
3-Acyloxymethylceph-3-em-4-carboxylic acids, for example cephalosporin C, are enzymically deacylated to their 3hydroxymethyl analogues by means of esterases produced by culturing a yeast microorganism or a mutant thereof of the genus Rhodotorula, for example a microorganism of the species Rhodotorula rubra. |