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filingDate 1973-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1975-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32cd8e2a0baf08ba89b14653c0f6fe4b
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publicationDate 1975-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-3905978-A
titleOfInvention 4R-amino-1t-phenyl-1c-ethoxycarbonyl-cyclohexenes-(2) and process for their preparation
abstract wherein R1 and R2 are the same or different and are hydrogen or alkyl having 1 to 4 carbon atoms, or one of the two groups is allyl, phenalkyl having 7 to 9 carbon atoms or Alpha -methylBeta -hydroxyethyl; or R1 and R2 together form a morpholino group, piperazino group substituted at the 4-position by methyl, benzyl, phenyl, 3-chlorophenyl, 4-chlorophenyl, 2-phenethyl or benzoyl, or a piperidino group substituted at the 4-position by hydroxyl, phenyl, 2-methoxyphenyl, 4-methoxyphenyl, methyl or benzyl and medically acceptable addition compounds derived from inorganic and organic acids or lower alkyl halides. The compounds of the present invention are prepared by separation of 4-amino-1phenyl-1-ethoxycarbonyl-cyclohexenes-(2), described in U.S. Pat. application Ser. No. 226,509, filed Feb. 15, 1972, into the two possible geometrical isomers. The instant compounds, the 4ramino-1t-phenyl-1c-ethoxycarbonyl-cyclohexenes-(2) of formula I, exhibit marked analgesic and neuroleptic activities and are useful for the alleviation and reduction of pain. This invention relates to 4r-amino-1t-phenyl-1c-ethoxycarbonylcyclohexenes-(2) of formula I:
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4061635-A
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priorityDate 1971-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 51.