http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3557127-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_334b26d249dc7a2d0df884c87eab5255 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-21 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-155 |
| filingDate | 1969-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1971-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0df32039d4994584ad6e9b251a12329d |
| publicationDate | 1971-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-3557127-A |
| titleOfInvention | Substituted cyclohexenes,derivatives thereof and processes for obtaining same |
| abstract | SUBSTITUTED CYCLOHEXENE BASES HAVING THE FORMULA: 3-(R1-N(-R2)-),4-PHENYL,4-R,R3-CYCLOHEXENE WHEREIN R IS CN, COR4 OR COOR4; WHEREIN R1 IS HYDROGEN OR A STRAIGHT OR BRANCHED CHAIN LOWER ALKYL RADICAL; WHEREIN R2 IS A STRAIGHT OR BRANCHED CHAIN LOWER ALKYL RADICAL OR WHEREIN THE ALKYL RADICALS REPRESENTED BY THE SYMBOLS R1 AND R2, TAKEN TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED, FORM A HETEROCYCLIC RING SYSTEM; WHEREIN R3 IS HYDROGEN OR A STRAIGHT OR BRANCHED CHAIN LOWER ALKYL RADICAL; AND WHEREIN R4 IS A STRAIGHT OR BRANCHED CHAIN LOWER ALKYL RADICAL AND MEDICINALLY ACEPTABLE ACID ADDITION SALTS THEREOF ARE DISCLOSED. DISCLOSED ALSO ARE CYCLOHEXYLAMINES DERIVED FROM CERTAIN OF THE FORMULA I COMPOUNDS; AN AMINO ALCOHOL DERIVED FROM A CYCLOHEXENE OF FORMULA I(A) AND AN AMINO ALCOHOL DERIVED FROM A CYCLOHEXYLAMINE OF FORMULA II; AND THE ACETYLATED DERIVATIVE OF THE LATTER AMINO ALCOHOL. THE COMPOUNDS OF THE INVENTION, I.E., THE CYCLOHEXENES OF FORMULA I AND THE AFOREMENTIONED DERIVATIVES THEREOF, EXHIBIT ANALGESIC ACTIVITY IN MAMMALS AND THEY ARE USED AS ANALGESICS. DISCLOSED ALSO ARE PROCESSES FOR OBTAINING THE FORMULA I COMPOUNDS IN THE FORM OF ISOMERIC MIXTURES; METHODS FOR SEPARATING THE CIS- AND TRANS-ISOMERS FROM THE ISOMERIC MIXTURES, PROCESSES FOR OBTAINING THE DISCLOSED CYCLOHEXYLAMINES, AMINO ALCOHOLS AND ACETYLATED DERIVATIVE; AND A METHOD FOR REARRANGING THE CIS-ISOMERS OF FORMULA I(A) TO THE TRANS-ISOMER. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4760146-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3905978-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4008233-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4022818-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9955662-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5693669-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4595759-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4061635-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9903821-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9903821-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-500119-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3957851-A |
| priorityDate | 1965-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.