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filingDate 2020-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020385296-A1
titleOfInvention Method for characterizing the prevalence of a biochemical condition within a population
abstract A method for estimating the prevalence of a biochemical condition in a population includes accessing, based on a wastewater sample collected by a wastewater sampling system that samples from a wastewater flow serving the population: a biochemical indicator concentration of a biochemical indicator characterized by a correlation of the biochemical indicator with the biochemical condition; and a biomarker concentration of a biomarker correlated with presence of human excreta. The method also includes: normalizing the biochemical indicator concentration based on the biomarker concentration; adjusting the biochemical indicator concentration based on decay characteristics of the biochemical indicator in wastewater; calculating a biochemical indicator mass estimate for the population based on the biochemical indicator concentration and an effective flow volume of the wastewater flow; and estimating a prevalence of the biochemical condition in the population based on the correlation of the biochemical indicator to the biochemical condition and the biochemical indicator mass estimate.
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