Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c50b17bd6ac893a28bee6b4bb8ead88 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b51672127cdd2721e4d540867de81f73 |
publicationDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2019177716-A1 |
titleOfInvention |
Ligand-guided-selection method for screening antigen-specific ligands |
abstract |
A Ligand-guided-Selection (LIGS) method for identifying highly specific aptamers against a predetermined antigen of a target is provided. LIGS uses a stronger and highly specific bivalent binder (e.g. an antibody) interacting with its cognate antigen to displace specific aptamers from an enriched SELEX pool. Elution of the displaced aptamers provides aptamers that are specific to the predetermined antigen. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110767262-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021019301-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110767262-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114480403-A |
priorityDate |
2015-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |