Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d42f684941d5b0617ca7764ebdff07 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate |
2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a16fea08441e8793083494294fabe88b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99f575e875c91ca9292ff39772b160a6 |
publicationDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2018230490-A1 |
titleOfInvention |
Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders |
abstract |
This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention a transgene product is delivered to a subject's spinal cord by administering a recombinant viral vector containing the transgene to the spinal cord. The viral vector delivers the transgene which expresses the encoded recombinant viral gene product. The viral gene product comprises HIF1-alpha. Also provided are compositions for delivery of a transgene product to a subject's spinal cord. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198873-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542506-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584337-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023288086-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10597660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10570395-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11193129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434502-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10920227-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603542-B2 |
priorityDate |
2006-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |