| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9a2af395ed1fdf11ba69df79f315432 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1252 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
| filingDate |
2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a9248925ad640e6187debb1a3a6d79d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd64cf3659243f1c527d93f6131eb961
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4cd2696a70166df5c3c736f022d884
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14a7096a89be9914b7953993d131cf1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef523c63b378a2b8d75946a6bedf7fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71981dca2aab49c2190c6e343aa4e234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81455c74fa030c8e8f26d72174a5578f |
| publicationDate |
2018-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2018119115-A1 |
| titleOfInvention |
Recombinant dna polymerase for improved incorporation of nucleotide analogues |
| abstract |
A composition comprising a recombinant DNA polymerase and 3′-esterified nucleotide analogues is provided. The recombinant DNA polymerase includes an amino acid sequence that is at least 90% homology with 9° N DNA polymerase (SEQ ID NO: 1), and the recombinant DNA polymerase includes at least two mutations at the positions corresponding to amino acid residues 141 and 143 of the 9° N DNA polymerase. A recombinant DNA polymerase is further provided. The recombinant DNA polymerase includes an amino acid sequence that is at least 90% homology with 9° N-III DNA polymerase (SEQ ID NO: 3), and the recombinant DNA polymerase includes one or two mutations at the positions corresponding to amino acid residue 480 and 486 of the 9° N-III DNA polymerase. A method of performing a polymerization reaction is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634697-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11560552-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11104888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11242512-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731141-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2574746-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2574746-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11001816-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020092830-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022194244-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112673098-A |
| priorityDate |
2016-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |