| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-103332
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-146666 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3346effd121d22b8d1df80fc72a6ae2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f645ca5b020c3892e59fd555f714ffa |
| publicationDate |
2016-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016169917-A1 |
| titleOfInvention |
Water soluble polyfluorene functionalized with glucuronic acid useful in bilirubin sensing |
| abstract |
The present invention provide water soluble polyfluorenes functionalized with glucuronic acid useful in sensing bilirubin in aqueous medium and process for preparation thereof. The invention further deals with detecting bilirubin in human serum samples in the range from normal (<25 μηioI/L˜1.2 mg/dL) human bilirubin level to jaundiced bilirubin level (>50 μηioI/L˜2.5 mg/dL). This is a fluorescence turn-off mode of detection where blue fluorescence of polymer quenches and becomes colorless. The water soluble polyfluorenes functionalized with glucuronic acid can detect free bilirubin in the range from 1×1O″4M to 1×10′7M moles in aqueous and buffer media as a change in the fluorescence signal. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110523387-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113640263-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896538-B2 |
| priorityDate |
2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |