Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0c660a867ae2188d9bf1df7ee8fdca3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82720f0fe09c6d788db8fde9be2350dc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-7783 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-78 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
filingDate |
2014-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4e47d0c96250cba95f7cd5a49fe9d8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb3b6c138ef17f310b991d35a7d8b89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271a7ca1ddc899fe1b175d134e0a7d44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d4d2aaa3d6e0abc2a5ed640256936c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_803645a6141e5e7785d5698ad2517e33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cb38a3450a6a25c12d1b31ccb20b2ee |
publicationDate |
2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016003858-A1 |
titleOfInvention |
Analyte extraction apparatus and method |
abstract |
Disclosed is a method and apparatus for determining a concentration of a glycopeptide antibiotic containing a phenol moiety such as Vancomycin in a complex sample matrix by extracting the glycopeptide antibiotic from a metered portion of the complex sample matrix by exposing said metered portion to an extraction material having an affinity with the glycopeptide antibiotic; and exposing the extraction material to a metered portion of an eluent for releasing the glycopeptide antibiotic from the extraction material; and by determining a concentration of the glycopeptide antibiotic by adding a Gibbs reagent (2,6 dichloroquinone-4chloroimide) to the metered portion of the complex sample matrix or the eluent; activating the Gibbs reagent and, after the reaction between the activated Gibbs reagent and the antibiotic has stabilized; detecting the reaction product of the activated Gibbs reagent and the antibiotic in said eluent; and determining the concentration of the antibiotic in the complex sample matrix from the detected reaction product. A method of designing a personalized drug administration regime using the thus obtained concentration is also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188783-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017151797-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10688239-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065378-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113945648-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019235994-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10786615-B2 |
priorityDate |
2013-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |