| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2013-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a537d8c812a62ee64ebc53fa69b55716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd32cd2449f8d92dd79ff76761dcc51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af226973a2cded1df8049b2cdb9fa5d4 |
| publicationDate |
2015-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015353630-A1 |
| titleOfInvention |
Antigen-binding molecule for eliminating aggregated antigens |
| abstract |
The present inventors discovered that incorporating an Fc region and an antigen-binding domain whose antigen-binding activity varies depending on ion concentration into an antigen-binding molecule that binds to an aggregate-forming antigen produces an antigen-binding molecule that can preferentially clear protein aggregates in comparison to protein monomers from plasma. Use of antigen-binding molecules of the present invention allows various diseases stemming from target tissues to be treated target-tissue-specifically. Use of antigen-binding molecules of the present invention enables treatment of diseases caused by protein aggregates. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629185-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359194-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11454633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10000560-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11371039-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11236168-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11718678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267868-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780912-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519229-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10253100-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11673947-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11608374-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9969800-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10023630-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662245-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018346605-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046784-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10738111-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919953-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267878-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9868948-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10774148-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890218-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180548-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766960-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10556949-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890377-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9765135-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10618965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11248053-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359009-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10472623-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597760-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385122-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11053308-B2 |
| priorityDate |
2012-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |