http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013252268-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_212a9505330ee201494a0d102ea80c7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06d423be7f94a530954c7a6b305117bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8aaab81f728a3f96f94b694ff453d657 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 |
| filingDate | 2013-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e5fb64441e01e9caead846b6981d8d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11aa284859df3fafbc09c6dcf0c1537c |
| publicationDate | 2013-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2013252268-A1 |
| titleOfInvention | Enzyme substrates for visualizing acidic organelles |
| abstract | The present invention relates to the visualization of acidic organelles based upon organelle enzyme activity. The organelle substrates of the invention are specific for enzyme activity of the organelle and label these organelles, such as lysosomes, rendering them visible and easily observed. Substrates of the present invention include substrates that produce a fluorescent signal. The fluorogenic acidic organelle enzyme substrates of this invention are designed to provide high fluorescence at low pH values and are derivatized to permit membrane permeation through both outer and organelle membranes of intact cells and can be used for staining cells at very low concentrations. They can be used for monitoring enzyme activity in cells at very low concentrations and are not toxic to living cells or tissues. |
| priorityDate | 2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1760.