http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013190483-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbd211e8dd496ddf7abf25a01d301cb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-281 |
| filingDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a419e43707fffbd71fd2249962f03ae3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_500987582613b1034a07229a9273e6bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9ac64ac0d8bf3335cc5f26e9ab2b32e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_390e4f31959db9dd025c1f83980c237c |
| publicationDate | 2013-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2013190483-A1 |
| titleOfInvention | Non-invasive detection of fetal genetic traits |
| abstract | Blood plasma of pregnant women contains fetal and (generally>90%) maternal circulatory extracellular DNA. Most of said fetal DNA contains ≦500 base pairs, said maternal DNA having a greater size. Separation of circulatory extracellular DNA of <500 base pairs results in separation of fetal from maternal DNA. A fraction of a blood plasma or serum sample of a pregnant woman containing, due to size separation (e.g. by chromatography, density gradient centrifugation or nanotechnological methods), extracellular DNA substantially comprising ≦500 base pairs is useful for non-invasive detection of fetal genetic traits (including the fetal RhD gene in pregnancies at risk for HDN; fetal Y chromosome-specific sequences in pregnancies at risk for X chromosome-linked disorders; chromosomal aberrations; hereditary Mendelian genetic disorders and corresponding genetic markers; and traits decisive for paternity determination) by e.g. PCR, ligand chain reaction or probe hybridization techniques, or nucleic acid arrays. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738931-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580751-B2 |
| priorityDate | 2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.