Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d2a00f2932d2f26f9bc4c81b9cd6345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c8512a8edc6e11c7f512df9589fafa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01dfac2cd07f2a5222250d75ce4ac269 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30ee6327e91f282decde74bbde0e4553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2bce701036e7d0c64f09e5c21c91c56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b39ed1c01608500e7b875aa7ebcf046 |
publicationDate |
2008-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008241828-A1 |
titleOfInvention |
Detection of dna methylation using raman spectroscopy |
abstract |
Epigenetic events such as DNA methylation play important roles in the regulation of gene expression. DNA methylation patterns have been found to differ between healthy and diseased tissue, such as healthy and cancerous tissue, thereby allowing DNA methylation to serve as a biomarker for disease states. Embodiments of the invention provide methods for detecting methylation patterns in DNA polymers. Methylation patterns are detected, in part, through the use of surface enhanced Raman spectroscopy (SERS). SERS provides a sensitive structure-based technique for chemical analysis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021743-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017066537-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018321156-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019017110-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11506610-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016205971-A1 |
priorityDate |
2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |