http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220442-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53d4035b9661d01264d635ecb2d65540 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2007-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_757467c217a443e6f20782fa184e3ee1 |
| publicationDate | 2008-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008220442-A1 |
| titleOfInvention | Difference detection methods using isoelectric focusing chips |
| abstract | The present invention provides an isoelectric focusing difference detection method, as well as an isoelectric focusing chip and device. The method entails labeling proteins in the first sample with a first label, and labeling proteins in the second sample with a second, different label, wherein each label has ionic and pH characteristics whereby, upon isoelectric focusing, relative migration of a protein labeled with the first label is substantially the same as relative migration of the same protein labeled with the second label. The samples are subjected to isoelectric focusing to produce a pattern of separated proteins from both samples, which is then detected to compare the protein composition of the samples. The method can be carried with a novel isoelectric focusing chip including a substrate comprising a channel for carrying out isolectric focusing. The substrate includes a non-fluorescent or low-fluorescence material in a detection region of the channel, facilitating direct detection of the pattern of separated proteins, which makes the chip particularly useful for clinical applications, including use disease diagnosis and monitoring. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10768141-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011071036-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011071051-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017044614-A1 |
| priorityDate | 2006-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.