Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
filingDate |
2008-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7183d40fc888c361ef2c16bde864e3aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3b740044cbf7c503fc645a78c2a79b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_169fecdd1a809f96232a3dd96f17b1f6 |
publicationDate |
2008-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008213796-A1 |
titleOfInvention |
GFP-SNAP25 Fluorescence Release Assay for Botulinum Toxin Protease Activity |
abstract |
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an affinity couple; and (iii) a portion of SNAP-25 that includes a BoNT/A, BoNT/C1 or BoNT/E recognition sequence containing a cleavage site, where the cleavage site intervenes between the green fluorescent protein and the first partner of the affinity couple. Further provided herein is a nucleic acid molecule which contains a nucleotide sequence encoding a tagged toxin substrate which includes (i) a fluorescent protein; (ii) a first partner of an affinity couple; and (iii) a clostridial toxin recognition sequence containing a cleavage site, where the cleavage site intervenes between the fluorescent protein and the first partner of the affinity couple. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008171348-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261240-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8198034-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7709608-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7678550-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170084098-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7749759-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010069610-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998749-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010055727-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332518-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007275477-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102409293-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008064054-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009042231-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009117572-A1 |
priorityDate |
2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |