| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2006-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c3384a5eb1a3d9038d7c218dca54f05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7183d40fc888c361ef2c16bde864e3aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66406059e1e9bcea4832a0c25e5dcf84 |
| publicationDate |
2008-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008146786-A1 |
| titleOfInvention |
Fret protease assays for botulinum serotype a/e toxins |
| abstract |
The present invention provides clostridial toxin substrates useful in assaying for the protease activity of any clostridial toxin, including botulinum toxins of all serotypes as well as tetanus toxins. A clostridial toxin substrate of the invention contains a donor fluorophore; an acceptor having an absorbance spectrum overlapping the emission spectrum of the donor fluorophore; and a clostridial toxin recognition sequence that includes a cleavage site, where the cleavage site intervenes between the donor fluorophore and the acceptor and where, under the appropriate conditions, resonance energy transfer is exhibited between the donor fluorophore and the acceptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009042231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8022172-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007243565-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220456-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846722-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008213796-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008171348-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008176249-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008166739-A1 |
| priorityDate |
2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |