http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206888-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dc9380e8825f2d95cbe9a28bfca490c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate | 2008-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_929cd2e740bcbae14b4acb66848f420e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d242a6d99f8dee8199fd91b52faee9e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9a15894163133697ed1ad251e6f6217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d33200160b399153854b721382556c9a |
| publicationDate | 2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008206888-A1 |
| titleOfInvention | Screening using polarization anisotropy in FRET emissions |
| abstract | Methods and apparatus are described for detecting specific binding between first and second chemical entities. The first chemical entity in association with a first fluorophore is immobilized. The second chemical entity is allowed to bind with the immobilized first chemical entity. The second chemical entity is or becomes coupled to a second fluorophore, which forms a FRET pair with the first fluorophore. The bound chemical entities are exposed to radiation at an excitation frequency for either the first or the second fluorophore, and polarization anisotropy of a FRET fluorescent signal from the bound chemical entities is measured to detect specific binding between the first and second chemical entities. Techniques are also disclosed for detecting whether a FRET interaction is occurring between a first chemical entity including a donor fluorophore and a second chemical entity including an acceptor fluorophore, using simultaneous anisotropy measurements at the wavelengths of the donor and acceptor fluorophores. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7674588-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9746470-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014315214-A1 |
| priorityDate | 2005-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.