http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008193968-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b61c1a5d7939b156db251749063a47e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7e42e3b0c724e3786222c6b567a9711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ddb4f0fc5c60e6a573466de0876c65a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00 |
| filingDate | 2006-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c926cbdaeda9110d98bb03cb96ec1a65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e0022222474c86b3ca6794a3166a581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e25f9be362f84a827c4d9a17d04eb57e |
| publicationDate | 2008-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2008193968-A1 |
| titleOfInvention | Therapeutic Uses of Artificial Nanostructures |
| abstract | The present invention provides a method for controlling the fate of mammalian cells or microorganisms by the enzymatic formation of intracellular nanostructures. Enzymatic reactions trigger the intracellular self-assembly to convert a proper precursor into another molecule or nanoobject that will aggregate inside cells or inside or between tissues or organs. Further, this invention provides a method for making artificial nanostructures inside or between tissues or organs, by injecting a proper designed precursor into tissues or organs, and enzymatic reaction converting the precursor to a hydrogelator to form artificial nanostructures and inducing hydrogelation and at the state of a disease, another enzyme converts the hydrogelator back to precursor to induce gel-to-sol transition to release a drug. The present invention can be applied to treat diseases caused by the malfunction of cells, infection caused by microorganisms and provides a novel route for controlled drug releases, formation of new therapeutic agents, and in-situ formation of hydrogel to treat degenerative diseases such as osteoarthritis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10093674-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012142616-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9408921-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012166706-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012166706-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014235550-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658600-B2 |
| priorityDate | 2005-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.