| abstract |
Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α 2 β 1 or α 5 β 1 integrin-specific ligand are provided. The substrates and devices coated with an α 2 β 1 or α 5 β 1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation. |