| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8216df9276cba113715f81a0d64a4d2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5214474ea5d114474d69bb1a0faefae9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de2491913639322e2fb2143402f9c637
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e9b5ccad326eb720d99dd3c2fb1273a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a704cf689fc6915db8df050f325e8a11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 |
| filingDate |
2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a755430478f6dbca95641b718edb66b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fe1b0fcf101f15fa5d9fb082847bf5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1664830a590e5a75988e5174e60810a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a15e6764d989ab100ea304dd6c48f03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f70e0449491975fc91a9f0eccf74e341 |
| publicationDate |
2008-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008090888-A2 |
| titleOfInvention |
Methods and materials for assessing prostate cancer therapies and compounds |
| abstract |
A modest (2-5 fold) increase in androgen receptor (AR) mRNA is the only expression change consistently associated with developing resistance to antiandrogen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low levels of residual ligand and altering the normal response to antagonists. This invention provides cell based assays for use in the examination of new therapeutic modalities and provides for the design of novel antiandrogen compounds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8450290-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011152348-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012065051-A1 |
| priorityDate |
2004-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |