| abstract |
Compounds having the Formula (I) or (III) wherein R 1 , R 2 and R 3 are each independently selected from H, OH, C 1-6 alkyl, C 1-6 alkoxy, NH 2 , NH—(C 1-6 alkyl), N(C 1-6 alkyl)(C 1-6 alkyl), SH, S—C 1-6 alkyl, NO 2 , CF 3 , OCF 3 , and halo; R 4 is unsubstituted Ar or Ar substituted with 1-4 substituents independently selected from C 1-6 alkyl, C 1-6 alkoxy and halo; X is selected from (CH 2 CH 2 O) n and (CH) n , and n=1-4, salts, solvates and hydrates thereof, useful for modulating or inhibiting cell proliferation, are described. |