Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c78dbed06cf729a4fd116d155e8aa1e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10 |
filingDate |
2004-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5466e11c460fb3212e697d887c59a3b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90db9c12c147e9853a6b5e45ba9559e |
publicationDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2007123489-A1 |
titleOfInvention |
Method and medicament for sulfated polysaccharide treatment of heparin-induced thrombocytopenia (HIT) syndrome |
abstract |
A method and medicament for treating and preventing platelet activation or thrombosis in the presence of heparin- and platelet factor 4-complex reactive antibodies using a 2-O desulfated heparin with an average degree of sulfation of 0.6 sulfate groups per monosaccharide or greater and an average molecular weight or 2.4 kD or greater. The medicament preferably is administered intravenously, by aerosolization or orally. Preferably, the 2-O desulfated heparin medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, normal saline, and distilled water. Additionally provided is a method of synthesizing 2-O desulfated heparin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200118510-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150023361-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10052346-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019236453-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009238852-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008138380-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7875596-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102165348-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229664-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102452803-B1 |
priorityDate |
2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |