| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87b1ba132642d628fc36060bc69d3ff9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-236 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 |
| filingDate |
2005-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8048ea81a88d1027817232597081a3a0 |
| publicationDate |
2005-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005261241-A1 |
| titleOfInvention |
Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses |
| abstract |
Dermatan sulfates and/or O-desulfated heparins useful in treating and preventing heparinoid-induced autoimmune responses, in particular heparin-induced thrombocytopenia (HIT) and its associated disease states. The dermatan sulfates comprise repeating disulfated and/or trisulfated disaccharide units of L-iduronic acid and N-acetyl-D-galactosamine. The O-desulfated heparins comprise heparin molecules selectively O-desulfated at the 2-O and/or 3-O positions of the uronic acid and glucosamine saccharide residues. Particularly effective dermatan sulfate HIT antagonists have a mean molecular weight of from about 2000 to about 10,000 Daltons. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7468358-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022082273-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012177715-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010255510-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10052346-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007123489-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229664-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9169315-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8940495-B2 |
| priorityDate |
2004-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |