http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007093556-A1

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filingDate 2004-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_049fdc14109a855b548a586fb023ccb5
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publicationDate 2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2007093556-A1
titleOfInvention Toremifene crystallization method
abstract The invention relates to a method for isolating toremifene from a mixture of toremifene and its corresponding E isomer. The method comprises contacting the isomer mixture with a first solvent comprising methanol, allowing toremifene to crystallize in said first solvent, allowing the crystallized product of the previous step to crystallize from a second solvent comprising acetone, methyl ethyl ketone or ethyl acetate, and optionally converting toremifene crystallized from the previous step to a pharmaceutically acceptable salt thereof.
priorityDate 2003-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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