abstract |
The chimeric empty viral-like particles derived from the infectious bursal disease virus (IBDV) are formed by the assembly of fusion proteins comprising a region A consisting of an IBDV pVP2 protein or a ā1-nā fragment of said IBDV pVP2, wherein ānā is an integer comprised between 441 and 501, bound to a region B consisting of a heterologous polypeptide comprising a polypeptide of interest, such as a polypeptide useful for prophylactic, therapeutic or diagnostic purposes. |