http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006263779-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9059fb91e79718057a75e72ddc8847b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2004-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86cadf479e9b8a0333b597c50e1f8213 |
| publicationDate | 2006-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2006263779-A1 |
| titleOfInvention | Method for the detection of cytosine methylation patterns with high sensitivity |
| abstract | The present invention concerns a method for the detection of cytosine methylation in DNA samples, in which the following steps are conducted: a genomic DNA sample which comprises target DNA and background DNA is chemically treated such that all unmethylated cytosine bases are converted to uracil, while the 5-methylcytosine bases remain unchanged; the chemically treated DNA sample is amplified with the use of at least 2 primer oligonucleotides as well as a polymerase and a nucleotide mixture, the composition of which leads to a preference for the target DNA over the background DNA as the template; and the methylation state in the target DNA is concluded from the presence of an amplificate or its quantity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011045542-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009186360-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010273151-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009123923-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10087482-B2 |
| priorityDate | 2003-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.