| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75545e2fb8e11207771caecda053beaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d74d0965170a8b3f46b76f0ee4bb0bff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56a5454de80db8f6d5d4f104305acccf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6913
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 |
| filingDate |
2006-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33cfbdbe5171cacfe42145af7525dabd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f092fee13551e825a60c914076b55de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b66a16ac86bfd7bc20fc438e6ac4d7a |
| publicationDate |
2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006240009-A1 |
| titleOfInvention |
Liposome composition for improved intracellular delivery of a therapeutic agent |
| abstract |
A liposomal composition and a method of using the same for achieving intracellular delivery of a liposome-entrapped agent is described. The liposomes are composed of a pH sensitive lipid and include a targeting ligand to direct the liposomes to a target cell. The liposomes also include a stabilizing component, such a polymer-derivatized lipid, where the polymer is attached to the lipid by a releasable linkage. Administration of the liposomes results in cellular internalization and destabilization of the liposome for intracellular delivery of the entrapped agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8343539-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9457041-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11696959-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8883989-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017172921-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014243391-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009280165-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009232883-A1 |
| priorityDate |
2001-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |