| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b63e00734c7dae2e2dccd070bb2c62cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39583 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 |
| filingDate |
2006-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5a31f01ec2136bb71829e6b71ac8136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14be20c6cb37e7a65c2335f1ee79ddcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca7fb7ab8adc1bf04f24e9d512727938 |
| publicationDate |
2006-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006239911-A1 |
| titleOfInvention |
Antibodies with immune effector activity and that internalize in endosialin-positive cells |
| abstract |
This invention relates to the use of monoclonal and polyclonal antibodies that specifically bind to and have the ability in the alternative to become internalized by cells expressing endosialin and to induce an immune effector activity such as antibody-dependent cellular cytotoxicity. The antibodies are useful in specific delivery of pharmacologic agents to endosialin-expressing cells as well as in eliciting an immune-effector activity particularly on tumor and neovascular cells and precursors. The invention is also related to nucleotides encoding the antibodies of the invention, cells expressing the antibodies; methods of detecting cancer and neovascular cells; and methods of treating cancer and neovascular disease using the antibodies, derivatives and fragments. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011033455-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10874728-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008248034-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010118203-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010021454-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9505842-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009104646-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016331819-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807382-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807416-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524237-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10053509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010118203-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2620451-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8389691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010260769-A1 |
| priorityDate |
2005-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |