| abstract |
Compounds of formula l: n n nand isomers, salts, solvates, chemically protected forms, and prodrugs thereof one of X 1 , X 2 and X 3 is N, and the others are CH; R N1 and R N2 together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms; R N3 and R N4 together with the nitrogen atom to which they are attached form a nitrogen-containing heterocyclic ring having from 4 to 8 ring atoms and their use in treating diseases ameliorated by the inhibition of mTOR. |