http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108623582-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2757891661e4d25e829bf22e69865f38 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6accd5e024df42d5a92f68a1ba701689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b04fc621d1efb7a1f563a9707d29646e |
| publicationDate | 2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108623582-A |
| titleOfInvention | A kind of preparation method of novel substituent-containing pyridopyrimidine compound |
| abstract | The invention belongs to the field of medicine and chemical industry, and specifically provides a preparation method of a novel substituent-containing pyridopyrimidine compound. Pyridopyrimidine compounds are of great significance in medical research and new drug development. The invention solves the problem that the amide compound is easily destroyed by a strong base under high temperature conditions during the synthesis process, and at the same time solves the problem that the amino group at the 4-position of pyrimidine is difficult to react to synthesize an amide due to the poor activity of the amino group, and the nitro group is reduced to an amino group. The two-step reaction with the hydrolysis of cyano group to amide is completed in one step reaction, which simplifies the reaction process. The invention provides a preparation method for this type of compound, and provides important support for the application of this type of compound in the field of future new drug development in terms of synthesis conditions, methods, techniques and the like. |
| priorityDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.