http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006166236-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09d3a89e938ea8276a0dc3f89949e00d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate | 2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8b7eda234b4b2fcbbdfdf7c0a0fba29 |
| publicationDate | 2006-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2006166236-A1 |
| titleOfInvention | Allosteric enzyme coupled immunoassay (AECIA) |
| abstract | The present invention is directed to methods and compositions for an allosteric enzyme coupled assay, and preferably to an allosteric enzyme coupled immunoassay (AECIA). The assay uses an allosteric enzyme to generate a readout signal. The assay is based on the competition between an analyte in a sample and an analyte or analyte analog conjugated to an allosteric regulator with a specific binding reagent for the analyte. In the absence of any analyte in the sample, an analyte or an analyte analog conjugated to an allosteric regulator binds to the specific binding reagent and such binding prevents or reduces the allosteric regulator's regulation, e.g., activation, on the allosteric enzyme. An analyte, if present in the sample, competes with the analyte or analyte analog conjugated to the allosteric regulator for binding with the specific binding reagent, reduces or prevents binding of the specific binding reagent to the analyte or analyte analog conjugated to the allosteric regulator, leading to increased regulation, e.g., activation, of the enzyme. 1-substituted-β-D-fructofuranose 2,6-bisphosphate compounds and conjugates comprising the same are provided. Kits comprising the conjugates, and methods using the conjugates for assaying an analyte are further provided. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109154602-A |
| priorityDate | 2004-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 683.