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filingDate 2005-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2006117399-A1
titleOfInvention Animal model for human lymphomas
abstract This invention develops the first mouse model for human lymphomas with mutations in the NF-KB2 gene that can be used for the study of the pathogenesis of this subset of lymphomas and for the development and testing of therapeutic and prevention drugs. The mice develop B- and T-cell lymphomas with extensive metastases in the liver, lung and kidneys, and can be used as an animal model for the development and testing of therapeutic/prevention drugs that target this group of human lymphoma patients.
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