| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76932e7ee8adb89af98465f5ac48435d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-775 |
| filingDate |
2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_942f3bb705cff6906d2be5931454fa20 |
| publicationDate |
2005-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005287636-A1 |
| titleOfInvention |
ProapolipoproteinA-I mutant and pharmaceutical composition comprising the same for prevention and treatment of atherosclerosis and hyperlipidemia |
| abstract |
The proapoA-I mutants of the present invention exhibit superior LDL-antioxidant activities over the wild-type proapoA-I and higher efficiencies for delivering cholesterol to hepatocytes than the previously reported apoA-I-R173C, and thus they can be effectively used for prevention and treatment of hyperlipidemia or atherosclerosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8791063-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8343932-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865644-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139640-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014011908-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9610324-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009050275-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9187550-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010222276-A1 |
| priorityDate |
2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |