Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c06d114257182ee7efd4c696c5fdb836 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate |
2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69801bdb4463e2b983f5b7987059efc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed58e10b713e2df2d223886155abd456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c4dee544e2f6e54ea2b40c34203a8fb |
publicationDate |
2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005282154-A1 |
titleOfInvention |
Angiotensin-converting enzyme-2 as a receptor for the SARS coronavirus |
abstract |
The present invention is based upon the identification of human angiotensin-converting enzyme-2 (ACE-2) as a functional receptor for the SARS coronavirus. Transfection of cells with ACE-2 confers upon them the ability to support viral replication. In addition, assays performed using ACE-2 together with the S protein of the SARS virus or a fragment derived from the S protein can be used to identify inhibitors that block the interaction between virus and host cell. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022184854-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021202456-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114252622-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022036049-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113156119-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111992186-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022159433-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021227994-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3925971-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021255067-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021202893-A1 |
priorityDate |
2003-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |