| abstract |
Systems and methods are provided for treatment of an eye. The systems generally include controlled, delayed and or sustained release bioerodible implantable elements having multiple layers of different materials and/or different concentrations of materials. The elements generally include an inner layer, or core, including a therapeutic agent, and one or more outer layers made of polymeric materials, for example substantially pure polymeric materials. The core may include a polymeric material combined with an active agent beneficial in treating a condition of an eye. The elements may be structured such that surfaces of the core are exposed to the physiological environment of the eye when initially implanted within the eye, or may be structured such that the core is entirely enclosed within the outer layers when initially implanted within the eye. |