| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84404c7a3ebbf9ac0fa0a63f72c714e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3653076ca7ebc08a7fc658e9bb34b956
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d58eb4c147f1820c93ecc7435b8729b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a76d52fa412e561281a89c27c2d8962 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate |
2003-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e093afdaa589f7881042bb1c66e3e6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68eb70c899a61f60c9eb88bad628b965
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83af4ed0223798bce2e73982d3895941
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5dee16f7d45d42f01af64540e14c1d4 |
| publicationDate |
2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005239074-A1 |
| titleOfInvention |
Hansenula polymorpha yapsin deficient mutant strain and process for the preparation of recombinant proteins using the same |
| abstract |
The present invention relates to a nucleic acid molecule comprising the HpYPS1 gene encoding H. polymorpha yapsin1, a polypeptide encoded by the nucleic acid molecule, a H. polymorpha mutant strain having reduced yapsin activity by mutation of the HpYPS gene encoding H. polymorpha yapsin1, a recombinant H. polymorpha strain expressing a foreign protein produced by introducing a gene encoding the foreign protein into the H. polymorpha mutant strain, and a process for preparing a foreign protein comprising culturing the recombinant H. polymorpha strain under conditions to express the foreign protein and isolating the foreign protein from the culture. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111315763-A |
| priorityDate |
2002-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |