Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6843 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5153 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate |
2004-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcadf7f12fec62ff3d2b5631911438de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_116288411a865a8986acde2cadcfa6f0 |
publicationDate |
2005-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005186264-A1 |
titleOfInvention |
Targeting drug/gene carriers to irradiated tissue |
abstract |
The present invention provides targeted delivery systems to deliver pharmaceuticals to irradiated tissue comprising a biomolecule carrier, a targeting moiety to cellular adhesion molecules and a pharmaceutical. The present invention also provides methods of selectively targeting endothelial tissue for delivery of a pharmaceutical thereto and of treating a pathophysiological state in an individual using the targeted delivery systems disclosed herein. Further provided is a method of optimizing an immunoliposome for specific targeting of a pharmaceutical encapsulated therein to irradiated tissue by selecting a liposome that has a greater rate of adhesion to the irradiated tissue than a rate of uptake by the reticuloendothelial system. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413281-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8808733-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018010202-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113616810-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9849087-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009108822-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10220000-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012035444-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9744187-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927379-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010098748-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017106010-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898506-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335428-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041153-B2 |
priorityDate |
2000-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |