| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
| filingDate |
2004-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39db6ca76ebe449fd3e94a91bace1942
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8606066f3d8f8424820e278557fbd72e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad9b0c48461c6d04ddb0c33fc438eb4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a6e1430411180883509dce167b58f78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b08b394a330308a716949f3435a7a5f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a62f1635f79e322c5a5ae3a5c7dbe43f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_495614799aaab3d9eb504e04753a555b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20682b5a42eed1623f4349bfcfd0806b |
| publicationDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005176085-A1 |
| titleOfInvention |
Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures |
| abstract |
The present invention describes a method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixture. The method comprises the selective isolation from every protein of those peptides that neither contain arginine nor histidine (NHNR peptides), and the determination of the relative concentrations of one or several proteins in different samples from the ratio between the areas of the estimated theoretical spectra for the NHNR peptides labeled with different isotopes in each sample. The determination of the relative concentration of proteins is valid for any type of isotopic label of the NHNR peptides. The method avoids the separation and purification of the proteins present in a complex mixture, and the analysis of all peptides generated from the enzymatic digest of the samples. The method is applicable to the identification of proteins with vacunal, therapeutic and diagnostic aims. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1785729-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8604692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10000545-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9110074-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1785729-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010317043-A1 |
| priorityDate |
2003-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |